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MedChemExpress non targeted dub loaded liposomes
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Non Targeted Dub Loaded Liposomes, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Croda International Plc liposomes dioleoyl sn glycerol 3 phosphoethanolamine dope
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Liposomes Dioleoyl Sn Glycerol 3 Phosphoethanolamine Dope, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BroadPharm dspe-peg-nhs liposomes
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Dspe Peg Nhs Liposomes, supplied by BroadPharm, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioMimetic Therapeutics peg coated liposomal encapsulation of dox
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Peg Coated Liposomal Encapsulation Of Dox, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher non-thermoresponsive liposomes dppc:cholesterol:dspe-peg 2k -n 3
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Non Thermoresponsive Liposomes Dppc:Cholesterol:Dspe Peg 2k N 3, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NanoCarrier Co liposome dspe-peg 2000 -tk-peg 5000
Establishment <t>of</t> <t>DUB-loaded</t> bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).
Liposome Dspe Peg 2000 Tk Peg 5000, supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sun Pharma pegylated liposome doxorubicin (hspc, dspe-peg, cholesterol)
List of approved nanomedicines for cancer treatment [ <xref ref-type= 23 , 26 , 47 - 59 ]" width="250" height="auto" />
Pegylated Liposome Doxorubicin (Hspc, Dspe Peg, Cholesterol), supplied by Sun Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millipore peg liposomes
List of approved nanomedicines for cancer treatment [ <xref ref-type= 23 , 26 , 47 - 59 ]" width="250" height="auto" />
Peg Liposomes, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Establishment of DUB-loaded bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).

Journal: Bioactive Materials

Article Title: Screening of a quinonoid compounds library identifies decylubiquinone as an antioxidant and anti-apoptotic agent against glucocorticoid-induced osteoporosis via CD39/CD73/adenosine axis

doi: 10.1016/j.bioactmat.2026.03.062

Figure Lengend Snippet: Establishment of DUB-loaded bone-targeted liposomal delivery system. ( A ) Representative images and quantitative analysis of mineralized nodule formation via Alizarin Red S (ARS) staining in primary BMSCs for the effect of DUB@Lip on osteogenesis differentiation under conditions of 10 μM Dex. ( B ) RT-qPCR for the expression of osteogenesis-related genes in primary BMSCs of different groups. ( C-D ) In vitro cellular uptake assay of IR-780-labeled DUB@Lip liposomes in primary BMSCs by confocal microscopy and flow cytometry. ( E-F ) Evaluation of bone-targeting capacity and pharmacokinetic analysis of DUB@Lip and DUB@TLip via ex vivo fluorescence imaging. ( G-H ) Representative reconstructed images and quantification for Tb.BV/TV, Tb.N, Tb.Th, Tb.Sp, and Ct.Th in femora in mice of different groups by Micro-CT. ( I ) H&E staining and quantification for trabecular bone area in distal femora in mice of different groups. ( J ) Masson staining and quantification for collagen deposition fraction (collagen area/trabecular bone area) in distal femora in mice of different groups. n = 4 independent repeats by using different biological samples in each group for in vitro experiments, or 8 mice per group for in vivo assays. Data were means ± s.e.m. ns p > 0.05, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by one-way ANOVA. Scale bars: 200 μm (A-B), 2 mm (G left & right bottom), 1 mm (G right top), and 100 μm (I-J).

Article Snippet: To prepare non-targeted DUB-loaded liposomes, DSPE-PEG2000-ALN was substituted with an equimolar amount of DSPE-mPEG2000 (HY-142978, MedChemExpress, Shanghai, China) using the same preparation procedure.

Techniques: Staining, Quantitative RT-PCR, Expressing, In Vitro, Labeling, Liposomes, Confocal Microscopy, Flow Cytometry, Ex Vivo, Fluorescence, Imaging, Micro-CT, In Vivo

List of approved nanomedicines for cancer treatment [ <xref ref-type= 23 , 26 , 47 - 59 ]" width="100%" height="100%">

Journal: Cancer Drug Resistance

Article Title: Recent advanced lipid-based nanomedicines for overcoming cancer resistance

doi: 10.20517/cdr.2024.19

Figure Lengend Snippet: List of approved nanomedicines for cancer treatment [ 23 , 26 , 47 - 59 ]

Article Snippet: 8 , PEGylated liposome doxorubicin (HSPC, DSPE-PEG, cholesterol) , Lipodox® , Sun Pharmaceutical Industries Ltd. , AIDS-associated Kaposi’s sarcoma, metastatic ovarian cancer, multiple myeloma , FDA (2013).

Techniques: Liposomes, Polymer